GLYATL2

glycine-N-acyltransferase-like 2

Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine (PubMed:22475485, PubMed:20305126).

Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging from chain-length C8:0-CoA to C18:0-CoA, to form a variety of N-acylglycines. Shows a preference for monounsaturated fatty acid oleoyl-CoA (C18:1-CoA) as an acyl donor. Does not exhibit any activity toward C22:6-CoA and chenodeoxycholoyl-CoA, nor toward serine or alanine (PubMed:20305126).

Long-chain fatty acid catabolic process Source: UniProtKB
Medium-chain fatty acid catabolic process Source: UniProtKB
Monounsaturated fatty acid catabolic process Source: UniProtKB

Endoplasmic reticulum

Acetylation at Lys-19 drastically decreases the production of N-oleoyl and N-arachidonoyl glycines.