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Mouse Anti-GLYATL2 Recombinant Antibody (1C5) (CBMAB-G3977-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1C5
Antibody Isotype
IgG
Application
ELISA, WB

Basic Information

Immunogen
GLYATL2 (AAH16789.1, aa1-294) full-length recombinant protein with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
glycine-N-acyltransferase-like 2
Entrez Gene ID
219970
UniProt ID
Q8WU03
Alternative Names
BXMAS2-10; GATF-B
Function
Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine (PubMed:22475485, PubMed:20305126).

Conjugates numerous substrates, such as arachidonoyl-CoA and saturated medium and long-chain acyl-CoAs ranging from chain-length C8:0-CoA to C18:0-CoA, to form a variety of N-acylglycines. Shows a preference for monounsaturated fatty acid oleoyl-CoA (C18:1-CoA) as an acyl donor. Does not exhibit any activity toward C22:6-CoA and chenodeoxycholoyl-CoA, nor toward serine or alanine (PubMed:20305126).
Biological Process
Long-chain fatty acid catabolic process Source: UniProtKB
Medium-chain fatty acid catabolic process Source: UniProtKB
Monounsaturated fatty acid catabolic process Source: UniProtKB
Cellular Location
Endoplasmic reticulum
PTM
Acetylation at Lys-19 drastically decreases the production of N-oleoyl and N-arachidonoyl glycines.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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