GATAD1

The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene.

Full Name

GATA Zinc Finger Domain Containing 1

Function

Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3).

Biological Process

Chromatin organization Source: GO_Central
Chromatin remodeling Source: GO_Central
Regulation of transcription, DNA-templated Source: InterPro

Cellular Location

Nucleus

Involvement in disease

Cardiomyopathy, dilated 2B (CMD2B):
A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Anti-GATAD1 antibodies

Mouse Anti-GATAD1 (AA 68-269) Recombinant Antibody (CBFYH-0260) (CBMAB-H1133-FY)

Datasheet

SDS

Target: GATAD1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYH-0260

Application*: WB

Mouse Anti-GATAD1 (AA 68-269) Recombinant Antibody (CBFYH-0259) (CBMAB-H1132-FY)

Datasheet

SDS

Target: GATAD1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYH-0259

Application*: WB

Mouse Anti-GATAD1 (AA 68-269) Recombinant Antibody (CBFYH-0258) (CBMAB-H1131-FY)

Datasheet

SDS

Target: GATAD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYH-0258

Application*: WB

Mouse Anti-GATAD1 Monoclonal Antibody (GATA9A1D3) (CBMAB-1433-YC)

Datasheet

SDS

Target: GATAD1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Mouse

Clone: GATA9A1D3

Application*: DB, F, IC, IF, WB

Mouse Anti-GATAD1 Recombinant Antibody (CBLG1-2618) (CBMAB-G2303-LY)

Datasheet

SDS

Target: GATAD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBLG1-2618

Application*: WB

Mouse Anti-GATAD1 Recombinant Antibody (8C155) (CBMAB-G2300-LY)

Datasheet

SDS

Target: GATAD1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: 8C155

Application*: WB

Mouse Anti-GATAD1 Recombinant Antibody (459C1a) (CBMAB-G2299-LY)

Datasheet

SDS

Target: GATAD1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 459C1a

Application*: DB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)