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Mouse Anti-GATAD1 Recombinant Antibody (459C1a) (CBMAB-G2299-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
459C1a
Antibody Isotype
IgG1
Application
Dot Blot

Basic Information

Immunogen
GATAD1 antibody was raised in mouse using recombinant Human Gata Zinc Finger Domain Containing 1 (Gatad1)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
140 mM NaCl
Preservative
0.05% sodium azide
Concentration
0.1 mg/mL
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
GATA Zinc Finger Domain Containing 1
Introduction
The protein encoded by this gene contains a zinc finger at the N-terminus, and is thought to bind to a histone modification site that regulates gene expression. Mutations in this gene have been associated with autosomal recessive dilated cardiomyopathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
Entrez Gene ID
57798
UniProt ID
Q8WUU5
Alternative Names
GATA Zinc Finger Domain Containing 1; Ocular Development-Associated Gene Protein; ODAG; GATA Zinc Finger Domain-Containing Protein 1; Ocular Development Associated Gene; RG083M05.2; CMD2B;
Function
Component of some chromatin complex recruited to chromatin sites methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3).
Biological Process
Chromatin organization Source: GO_Central
Chromatin remodeling Source: GO_Central
Regulation of transcription, DNA-templated Source: InterPro
Cellular Location
Nucleus
Involvement in disease
Cardiomyopathy, dilated 2B (CMD2B):
A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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