FOXJ2

FOXJ2 (Forkhead Box J2) is a Protein Coding gene. Diseases associated with FOXJ2 include Cardiomyopathy, Familial Hypertrophic, 3. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is FOXJ3.

FOXJ2

Isoform FOXJ2.L:
Transcriptional activator. Able to bind to two different type of DNA binding sites. More effective than isoform FOXJ2.S in transcriptional activation (PubMed:10777590, PubMed:10966786).

Plays an important role in spermatogenesis, especially in spermatocyte meiosis (By similarity).

Isoform FOXJ2.S:
Transcriptional activator.

Cell differentiation Source: UniProtKB-KW
Male meiosis I Source: UniProtKB
Negative regulation of angiogenesis Source: BHF-UCL
Negative regulation of blood vessel endothelial cell differentiation Source: BHF-UCL
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Positive regulation of vascular associated smooth muscle cell proliferation Source: BHF-UCL
Regulation of transcription by RNA polymerase II Source: GO_Central
Spermatogenesis Source: UniProtKB

Nucleus