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FOSB

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Full Name

FOSB

Function

FosB interacts with Jun proteins enhancing their DNA binding activity.

Biological Process

Cellular response to calcium ion Source: Ensembl
Cellular response to hormone stimulus Source: Ensembl
Female pregnancy Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: ProtInc
Regulation of transcription by RNA polymerase II Source: GO_Central
Response to cAMP Source: Ensembl
Response to corticosterone Source: Ensembl
Response to drug Source: Ensembl
Response to mechanical stimulus Source: Ensembl
Response to morphine Source: Ensembl
Response to progesterone Source: Ensembl
Transcription by RNA polymerase II Source: Ensembl

Cellular Location

Nucleus

Anti-FOSB antibodies

Mouse Anti-FOSB Antibody (1D8) (CBMAB-0372-YC)

SDS

Target: FOSB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1D8

Application*: IP, M

Mouse Anti-FOSB Antibody (1C9) (CBMAB-0371-YC)

SDS

Target: FOSB

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 1C9

Application*: IP, WB, M

Mouse Anti-FOSB (AA 2-15) Recombinant Antibody (CBXF-3124) (CBMAB-F3820-CQ)

SDS

Target: FOSB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-3124

Application*: WB

Rabbit Anti-FOSB Recombinant Antibody (CBXF-3123) (CBMAB-F3819-CQ)

SDS

Target: FOSB

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: CBXF-3123

Application*: F

Mouse Anti-FOSB Recombinant Antibody (CBXF-1763) (CBMAB-F3298-CQ)

SDS

Target: FOSB

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBXF-1763

Application*: WB, IP, IF, P, E

Mouse Anti-FOSB Recombinant Antibody (CBXF-1761) (CBMAB-F3296-CQ)

SDS

Target: FOSB

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBXF-1761

Application*: WB, IP, IF, E

Mouse Anti-FOSB (AA 1-338) Recombinant Antibody (CBXF-2656) (CBMAB-F3071-CQ)

SDS

Target: FOSB

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Mouse

Clone: CBXF-2656

Application*: WB

Mouse Anti-FOSB Recombinant Antibody (CBXF-2350) (CBMAB-F2820-CQ)

SDS

Target: FOSB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-2350

Application*: IP

Mouse Anti-FOSB Recombinant Antibody (CBXF-2351) (CBMAB-F2819-CQ)

SDS

Target: FOSB

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXF-2351

Application*: IP, WB

Rabbit Anti-FOSB Recombinant Antibody (CBXF-2249) (CBMAB-F2638-CQ)

SDS

Target: FOSB

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBXF-2249

Application*: CI, F, IF, P, IP, WB

Mouse Anti-FOSB (AA 1-255) Recombinant Antibody (CBXF-3593) (CBMAB-F2522-CQ)

SDS

Target: FOSB

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBXF-3593

Application*: WB

Mouse Anti-FOSB (AA 2-15) Recombinant Antibody (CBXF-0819) (CBMAB-F2443-CQ)

SDS

Target: FOSB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-0819

Application*: WB

Mouse Anti-FOSB (AA 1-255) Recombinant Antibody (CBXF-3679) (CBMAB-F2064-CQ)

SDS

Target: FOSB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBXF-3679

Application*: WB

Rabbit Anti-FOSB Recombinant Antibody (CBXF-3739) (CBMAB-F1407-CQ)

SDS

Target: FOSB

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBXF-3739

Application*: WB, IP, P, IF, F, CI

Mouse Anti-FOSB Recombinant Antibody (83B1138) (CBMAB-F0937-CQ)

SDS

Target: FOSB

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat

Clone: 83B1138

Application*: WB, F

Rabbit Anti-FOSB Recombinant Antibody (CBYCD-473) (CBMAB-D2075-YC)

SDS

Target: FOSB

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat, Monkey

Clone: CBYCD-473

Application*: WB, IP

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

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