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FOSB

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Full Name
FOSB
Function
FosB interacts with Jun proteins enhancing their DNA binding activity.
Biological Process
Cellular response to calcium ion Source: Ensembl
Cellular response to hormone stimulus Source: Ensembl
Female pregnancy Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: ProtInc
Regulation of transcription by RNA polymerase II Source: GO_Central
Response to cAMP Source: Ensembl
Response to corticosterone Source: Ensembl
Response to drug Source: Ensembl
Response to mechanical stimulus Source: Ensembl
Response to morphine Source: Ensembl
Response to progesterone Source: Ensembl
Transcription by RNA polymerase II Source: Ensembl
Cellular Location
Nucleus

Anti-FOSB antibodies

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Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D8
Application*: IP, M
Target: FOSB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1C9
Application*: IP, WB, M
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3124
Application*: WB
Target: FOSB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBXF-3123
Application*: F
Target: FOSB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1763
Application*: WB, IP, IF, P, E
Target: FOSB
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-1761
Application*: WB, IP, IF, E
Target: FOSB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: CBXF-2656
Application*: WB
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-2350
Application*: IP
Target: FOSB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-2351
Application*: IP, WB
Target: FOSB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-2249
Application*: CI, F, IF, P, IP, WB
Target: FOSB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXF-3593
Application*: WB
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-0819
Application*: WB
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3679
Application*: WB
Target: FOSB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBXF-3739
Application*: WB, IP, P, IF, F, CI
Target: FOSB
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 83B1138
Application*: WB, F
Target: FOSB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Monkey
Clone: CBYCD-473
Application*: WB, IP
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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