EGFL7

This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Full Name

EGF Like Domain Multiple 7

Research Area

Regulates vascular tubulogenesis in vivo. Inhibits platelet-derived growth factor (PDGF)-BB-induced smooth muscle cell migration and promotes endothelial cell adhesion to the extracellular matrix and angiogenesis.

Biological Process

Anatomical structure development Source: GO_Central
Angiogenesis Source: UniProtKB-KW
Blood vessel development Source: UniProtKB
Cell adhesion Source: UniProtKB-KW
Negative regulation of Notch signaling pathway Source: MGI
Positive regulation of endothelial cell proliferation Source: MGI
Vasculogenesis Source: UniProtKB

Cellular Location

Extracellular space

Anti-EGFL7 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-EGFL7 Recombinant Antibody (3G1) (CBMAB-A2494-LY)

Datasheet

SDS

Target: EGFL7

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 3G1

Application*: SE, E

Mouse Anti-EGFL7 Recombinant Antibody (2H6) (CBMAB-A2493-LY)

Datasheet

SDS

Target: EGFL7

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: 2H6

Application*: WB, E

Rat Anti-EGFL7 (N-Terminus) Recombinant Antibody (CBYY-1024) (CBMAB-1028-YY)

Datasheet

SDS

Target: EGFL7

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: CBYY-1024

Application*: E, WB

Mouse Anti-EGFL7 Recombinant Antibody (CBFYE-0543) (CBMAB-E0908-FY)

Datasheet

SDS

Target: EGFL7

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYE-0543

Application*: E, IH, WB

Mouse Anti-EGFL7 (AA 24-273) Recombinant Antibody (CBFYE-0542) (CBMAB-E0907-FY)

Datasheet

SDS

Target: EGFL7

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBFYE-0542

Application*: E, WB

Mouse Anti-EGFL7 (AA 24-273) Recombinant Antibody (CBFYE-0541) (CBMAB-E0906-FY)

Datasheet

SDS

Target: EGFL7

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYE-0541

Application*: IH

Mouse Anti-EGFL7 (AA 24-273) Recombinant Antibody (CBFYE-0540) (CBMAB-E0905-FY)

Datasheet

SDS

Target: EGFL7

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYE-0540

Application*: WB

Mouse Anti-EGFL7 Recombinant Antibody (CBFYE-0043) (CBMAB-E0097-FY)

Datasheet

SDS

Target: EGFL7

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYE-0043

Application*: E, WB

EGFL7 Matched Antibody Pair (370) (APMAB-370LY)

Datasheet

SDS

Target: EGFL7

Specificity: Human

EGFL7 Matched Antibody Pair (369) (APMAB-369LY)

Datasheet

SDS

Target: EGFL7

Specificity: Human

EGFL7 Matched Antibody Pair (368) (APMAB-368LY)

Datasheet

SDS

Target: EGFL7

Specificity: Human

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)