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EGFL7 Matched Antibody Pair (370) (APMAB-370LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-EGFL7 polyclonal antibody, 100 ug
Detection Antibody
Anti-EGFL7 Mouse monoclonal, IgG2a antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a secreted endothelial cell protein that contains two epidermal growth factor-like domains. The encoded protein may play a role in regulating vasculogenesis. This protein may be involved in the growth and proliferation of tumor cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]
Alternative Names
EGF Like Domain Multiple 7; Multiple Epidermal Growth Factor-Like Domains Protein 7; Multiple EGF-Like Domains Protein 7; Vascular Endothelial Statin; NOTCH4-Like Protein; EGF-Like Protein 7; VE-STATIN;
Entrez Gene ID
51162
UniProt ID
Q9UHF1
More Infomation

Ortega, M. A., Asunsolo, A., Fraile‑Martínez, O., Sainz, F., Saez, M. A., Bravo, C., ... & García‑Honduvilla, N. (2021). An increase in elastogenic components in the placental villi of women with chronic venous disease during pregnancy is associated with decreased EGFL7 expression level. Molecular medicine reports, 24(2), 1-9.

Heissig, B., Salama, Y., Takahashi, S., Okumura, K., & Hattori, K. (2021). The multifaceted roles of EGFL7 in cancer and drug resistance. Cancers, 13(5), 1014.

Massimiani, M., Salvi, S., Tiralongo, G. M., Moresi, S., Stuhlmann, H., Valensise, H., ... & Campagnolo, L. (2021). Circulating EGFL7 distinguishes between IUGR and PE: An observational case–control study. Scientific Reports, 11(1), 1-8.

Bill, M., Pathmanathan, A., Karunasiri, M., Shen, C., Burke, M. H., Ranganathan, P., ... & Dorrance, A. M. (2020). EGFL7 Antagonizes NOTCH Signaling and Represents a Novel Therapeutic Target in Acute Myeloid LeukemiaTargeting EGFL7 in AML. Clinical Cancer Research, 26(3), 669-678.

Liu, Q., He, H., Yuan, Y., Zeng, H., Wang, Z., & Luo, W. (2020). Novel expression of EGFL7 in osteosarcoma and sensitivity to cisplatin. Frontiers in Oncology, 10, 74.

Usuba, R., Pauty, J., Soncin, F., & Matsunaga, Y. T. (2019). EGFL7 regulates sprouting angiogenesis and endothelial integrity in a human blood vessel model. Biomaterials, 197, 305-316.

Richter, A., Alexdottir, M. S., Magnus, S. H., Richter, T. R., Morikawa, M., Zwijsen, A., & Valdimarsdottir, G. (2019). EGFL7 mediates BMP9-induced sprouting angiogenesis of endothelial cells derived from human embryonic stem cells. Stem cell reports, 12(6), 1250-1259.

Larochelle, C., Uphaus, T., Broux, B., Gowing, E., Paterka, M., Michel, L., ... & Zipp, F. (2018). EGFL7 reduces CNS inflammation in mouse. Nature communications, 9(1), 1-12.

Dudvarski Stanković, N., Bicker, F., Keller, S., Jones, D. T., Harter, P. N., Kienzle, A., ... & Schmidt, M. H. (2018). EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors. EMBO molecular medicine, 10(9), e8420.

Hong, G., Kuek, V., Shi, J., Zhou, L., Han, X., He, W., ... & Xu, J. (2018). EGFL7: Master regulator of cancer pathogenesis, angiogenesis and an emerging mediator of bone homeostasis. Journal of cellular physiology, 233(11), 8526-8537.

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For research use only. Not intended for any clinical use.

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