CTSH

CTSH (Cathepsin H) is a Protein Coding gene. Diseases associated with CTSH include Thyroid Crisis and Intermittent Explosive Disorder. Among its related pathways are Innate Immune System and Surfactant metabolism. Gene Ontology (GO) annotations related to this gene include protein complex binding and peptidase activity. An important paralog of this gene is CTSK.

Cathepsin H

Important for the overall degradation of proteins in lysosomes.

Adaptive immune response Source: UniProtKB
Antigen processing and presentation Source: UniProtKB
Bradykinin catabolic process Source: UniProtKB
Cellular protein metabolic process Source: Reactome
Cellular response to thyroid hormone stimulus Source: UniProtKB
Dichotomous subdivision of terminal units involved in lung branching Source: UniProtKB
ERK1 and ERK2 cascade Source: UniProtKB
Immune response-regulating signaling pathway Source: UniProtKB
Membrane protein proteolysis Source: UniProtKB
Metanephros development Source: UniProtKB
Negative regulation of apoptotic process Source: UniProtKB
Neuropeptide catabolic process Source: UniProtKB
Neutrophil degranulation Source: Reactome
Positive regulation of angiogenesis Source: UniProtKB
Positive regulation of cell migration Source: UniProtKB
Positive regulation of cell population proliferation Source: UniProtKB
Positive regulation of epithelial cell migration Source: UniProtKB
Positive regulation of gene expression Source: UniProtKB
Positive regulation of peptidase activity Source: UniProtKB
Protein destabilization Source: UniProtKB
Proteolysis Source: UniProtKB
Proteolysis involved in cellular protein catabolic process Source: GO_Central
Response to retinoic acid Source: UniProtKB
Surfactant homeostasis Source: UniProtKB
T cell mediated cytotoxicity Source: UniProtKB
Zymogen activation Source: UniProtKB

Lysosome