CTBP2

CTBP2 (C-Terminal Binding Protein 2) is a Protein Coding gene. Diseases associated with CTBP2 include Retinitis Pigmentosa 14 and Deafness, Autosomal Recessive 9. Among its related pathways are Chronic myeloid leukemia and Mesodermal Commitment Pathway. Gene Ontology (GO) annotations related to this gene include chromatin binding and transcription corepressor activity. An important paralog of this gene is CTBP1.

C-Terminal Binding Protein 2

Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity).

Isoform 2 probably acts as a scaffold for specialized synapses.

Cellular response to leukemia inhibitory factor Source: Ensembl
Negative regulation of cell population proliferation Source: ProtInc
Negative regulation of transcription, DNA-templated Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: ARUK-UCL
Positive regulation of chromatin binding Source: Ensembl
Positive regulation of retinoic acid receptor signaling pathway Source: MGI
Positive regulation of transcription by RNA polymerase II Source: MGI
Synaptic vesicle docking Source: Ensembl
Viral genome replication Source: ProtInc
White fat cell differentiation Source: UniProtKB

Nucleus; Synapse