CNN1

CNN1 (Calponin 1) is a Protein Coding gene. Diseases associated with CNN1 include Laryngeal Small Cell Carcinoma and Infantile Digital Fibromatosis. Among its related pathways are Myometrial Relaxation and Contraction Pathways and Endothelin Pathways. Gene Ontology (GO) annotations related to this gene include actin binding and calmodulin binding. An important paralog of this gene is CNN3.

Full Name

Calponin 1

Function

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).

Biological Process

Actomyosin structure organization Source: InterPro
Negative regulation of vascular associated smooth muscle cell proliferation Source: BHF-UCL
Regulation of smooth muscle contraction Source: UniProtKB

Cellular Location

Cytoskeleton; Focal adhesion

Anti-CNN1 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-CNN1 Recombinant Antibody (CBXC-0489) (CBMAB-C5142-CQ)

Datasheet

SDS

Target: CNN1

Host: Mouse

Antibody Isotype: IgG3

Specificity: Human

Clone: CBXC-0489

Application*: IH, WB, IF

Mouse Anti-CNN1 Recombinant Antibody (2F5-1H4) (CBMAB-C5108-LY)

Datasheet

SDS

Target: CNN1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: 2F5-1H4

Application*: E, P, WB

Mouse Anti-CNN1 Recombinant Antibody (0-N-39) (CBMAB-C1893-LY)

Datasheet

SDS

Target: CNN1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: 0-N-39

Application*: WB, IP, IF, P

Rabbit Anti-CNN1 Recombinant Antibody (CBCNC-224) (V2LY-1206-LY439)

Datasheet

SDS

Target: CNN1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBCNC-224

Application*: P

Mouse Anti-CNN1 Recombinant Antibody (CBWJC-2854) (V2LY-1206-LY438)

Datasheet

SDS

Target: CNN1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBWJC-2854

Application*: E, P, WB

Mouse Anti-CNN1 Recombinant Antibody (CBWJC-2853) (V2LY-1206-LY437)

Datasheet

SDS

Target: CNN1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Rat

Clone: CBWJC-2853

Application*: IH, IF, F

Rabbit Anti-CNN1 Recombinant Antibody (CBWJC-2047) (V2LY-1206-LY436)

Datasheet

SDS

Target: CNN1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Rat

Clone: CBWJC-2047

Application*: IH, IF, F

Mouse Anti-CNN1 Recombinant Antibody (CBXC-2753) (V2LY-1206-LY435)

Datasheet

SDS

Target: CNN1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Rat

Clone: CBXC-2753

Application*: IH, WB, IF, F

Mouse Anti-CNN1 Recombinant Antibody (CBXC-1376) (V2LY-1206-LY433)

Datasheet

SDS

Target: CNN1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Rat

Clone: CBXC-1376

Application*: F, WB, IH

Mouse Anti-CNN1 Recombinant Antibody (CBXC-2706) (V2LY-1206-LY432)

Datasheet

SDS

Target: CNN1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Rat

Clone: CBXC-2706

Application*: F, IF, IH

Mouse Anti-CNN1 Recombinant Antibody (CBYY-C0677) (V2LY-1206-LY431)

Datasheet

SDS

Target: CNN1

Host: Mouse

Antibody Isotype: IgM, κ

Specificity: Human

Clone: CBYY-C0677

Application*: E, WB

Mouse Anti-CNN1 Recombinant Antibody (CBFYC-1987) (V2LY-1206-LY430)

Datasheet

SDS

Target: CNN1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat

Clone: CBFYC-1987

Application*: WB, IP, IF, P

CNN1 Matched Antibody Pair (282) (APMAB-282LY)

Datasheet

SDS

Target: CNN1

Specificity: Human

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)