CDH17

CDH17 (Cadherin 17) is a Protein Coding gene. Diseases associated with CDH17 include Gastric Cancer and Gastric Adenocarcinoma. Among its related pathways are ERK Signaling and Gastric cancer. Gene Ontology (GO) annotations related to this gene include calcium ion binding and proton-dependent oligopeptide secondary active transmembrane transporter activity. An important paralog of this gene is CDH16.

Cadherin 17

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport.

Adherens junction organization Source: Reactome
Calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules Source: UniProtKB
Cell adhesion Source: ProtInc
Cell-cell adhesion via plasma-membrane adhesion molecules Source: GO_Central
Germinal center B cell differentiation Source: Ensembl
Homophilic cell adhesion via plasma membrane adhesion molecules Source: UniProtKB
Integrin-mediated signaling pathway Source: UniProtKB
Marginal zone B cell differentiation Source: Ensembl
Oligopeptide transmembrane transport Source: UniProtKB
Oligopeptide transport Source: UniProtKB
Positive regulation of integrin activation by cell surface receptor linked signal transduction Source: UniProtKB
Spleen development Source: Ensembl

Cell membrane

Extracellular: 23-787
Helical: 788-808
Cytoplasmic: 809-832