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CD1d

CD1D (CD1d Molecule) is a Protein Coding gene. Diseases associated with CD1D include Mycobacterium Malmoense and Autoimmune Disease. Among its related pathways are Innate Immune System and Amoebiasis. Gene Ontology (GO) annotations related to this gene include receptor activity and cell adhesion molecule binding. An important paralog of this gene is CD1E.
Full Name
CD1d Molecule
Alternative Names
CD1d Molecule; CD1D Antigen, D Polypeptide; CD1d Antigen; R3G1; HMC Class I Antigen-Like Glycoprotein CD1D; Antigen-Presenting Glycoprotein CD1d;
Function
Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
Biological Process
Antigen processing and presentation, endogenous lipid antigen via MHC class Ib Source: UniProtKB
Antigen processing and presentation, exogenous lipid antigen via MHC class Ib Source: GO_Central
Detection of bacterium Source: UniProtKB
Heterotypic cell-cell adhesion Source: BHF-UCL
Innate immune response Source: UniProtKB-KW
Positive regulation of innate immune response Source: UniProtKB
Positive regulation of T cell mediated cytotoxicity Source: GO_Central
Positive regulation of T cell proliferation Source: BHF-UCL
Regulation of immune response Source: Reactome
T cell selection Source: UniProtKB
Cellular Location
Lysosome membrane; Endoplasmic reticulum membrane; Endosome membrane; Cell membrane; Basolateral cell membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.
Topology
Extracellular: 20-301
Helical: 302-322
Cytoplasmic: 323-335

Anti-CD1d antibodies

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Target: CD1d
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Mouse
Clone: AG08
Application*: In Vivo, IP, WB
Target: CD1D
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: C3D5
Application*: IF, P, IP, WB
Target: CD1D
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: NOR3.2
Application*: IF, P, IP, WB
Target: CD1D
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: C1590
Application*: IF, E, IP, WB
Target: CD1D
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXC-0185
Application*: IF, E, IP, WB
Target: CD1D
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat
Clone: CBXC-0184
Application*: IF, E, IP, WB
Target: CD1D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-C1219
Application*: E, WB, IH
Target: CD1D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-1137
Application*: E, WB, F
Target: CD1D
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 1B1
Application*: F, IP, IH
Target: CD1D
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3H649
Application*: IF, P, IP, WB
Target: CD1d
Host: Rat
Antibody Isotype: IgG1
Specificity: Mouse
Clone: 19G11
Application*: N, in vivo
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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