CD151

CD151 (CD151 Molecule (Raph Blood Group)) is a Protein Coding gene. Diseases associated with CD151 include Nephropathy With Pretibial Epidermolysis Bullosa And Deafness and Raph Blood Group System. Among its related pathways are Primary Focal Segmental Glomerulosclerosis FSGS and Collagen chain trimerization. Gene Ontology (GO) annotations related to this gene include integrin binding. An important paralog of this gene is TSPAN11.

CD151 Molecule (Raph Blood Group)

CD151 Molecule (Raph Blood Group); CD151 Antigen; Platelet-Endothelial Tetraspan Antigen 3; CD151 Antigen (Raph Blood Group); Membrane Glycoprotein SFA-1; Tetraspanin-24; Tspan-24; TSPAN24; PETA-3;

Essential for the proper assembly of the glomerular and tubular basement membranes in kidney.
(Microbial infection) Plays a role in human papillomavirus 16/HPV-16 endocytosis upon binding to cell surface receptor.

Cell adhesion Source: ProtInc
Cell migration Source: GO_Central
Collagen fibril organization Source: Reactome
Hemidesmosome assembly Source: Reactome
Positive regulation of cell migration Source: MGI
Positive regulation of endocytosis Source: MGI
T cell proliferation Source: Ensembl
Viral process Source: UniProtKB-KW
Wound healing, spreading of cells Source: MGI

Membrane

Nephropathy with pretibial epidermolysis bullosa and deafness (NPEBD): A disorder characterized by the association of hereditary nephritis, epidermolysis bullosa, deafness, and beta-thalassemia minor.

Cytoplasmic: 1-18
Helical: 19-39
Extracellular: 40-57
Helical: 58-78
Cytoplasmic: 79-91
Helical: 92-112
Extracellular: 113-221
Helical: 222-242
Cytoplasmic: 243-253

Palmitoylated. Palmitoylation by ZDHHC2 regulates CD151 expression, association with other tetraspanin family proteins and function in cell adhesion.