ARTN

ARTN is a secreted ligand of the glial cell line-derived neurotrophic factor (GDNF) subfamily and TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activat

Artemin

Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex. Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue.

Axon guidance Source: Reactome
Induction of positive chemotaxis Source: Ensembl
Lymphocyte migration into lymphoid organs Source: Ensembl
MAPK cascade Source: Reactome
Neuroblast proliferation Source: ProtInc
Peripheral nervous system development Source: GO_Central
Peyer's patch morphogenesis Source: Ensembl
Signal transduction Source: ProtInc

Secreted