ANGPTL7

ANGPTL7 (Angiopoietin Like 7) is a Protein Coding gene. An important paralog of this gene is ANGPT4.

Angiopoietin Like 7

Has a role in the formation and organization of the extracellular matrix. In the eye, it functions as a mediator of dexamethasone-induced matrix deposition in the trabecular meshwork, the tissue responsible for the outflow of the ocular aqueous humor and for the maintenance of intraocular pressure (PubMed:21199193). Is a negative regulator of angiogenesis in the cornea, and plays a major role in maintaining corneal avascularity and transparency (PubMed:25622036).

Angiogenesis Source: GO_Central
Negative regulation of vasculature development involved in avascular cornea development in camera-type eye Source: UniProtKB
Regulation of extracellular matrix organization Source: UniProtKB
Response to oxidative stress Source: ProtInc

Secreted