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RFXANK Matched Antibody Pair (988) (APMAB-988LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-RFXANK monoclonal antibody, 100 ug
Detection Antibody
Anti-RFXANK Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group B. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2013]
Alternative Names
Regulatory Factor X Associated Ankyrin Containing Protein; Regulatory Factor X Subunit B; Ankyrin Repeat-Containing Regulatory Factor X-Associated Protein; Regulatory Factor X-Associated Ankyrin-Containing Protein; Ankyrin Repeat Family A Protein 1; DNA-Binding Protein RFXANK; RFX-Bdelta4;
Entrez Gene ID
8625
UniProt ID
O14593
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For research use only. Not intended for any clinical use.

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