NME1 Matched Antibody Pair (803) (APMAB-803LY)

See all NME1 antibodies

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-NME1 polyclonal antibody, 100 ug

Detection Antibody

Anti-NME1 Mouse monoclonal, IgG1 antibody, 20 ug

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]

Alternative Names

NME/NM23 Nucleoside Diphosphate Kinase 1; Non-Metastatic Cells 1, Protein (NM23A) Expressed In; Tumor Metastatic Process-Associated Protein; Metastasis Inhibition Factor Nm23; Granzyme A-Activated DNase; NDP Kinase A; EC 2.7.4.6; NM23-H1; NDPKA; GAAD;

Entrez Gene ID

4830

UniProt ID

P15531

More Infomation

References

Iuso, D., Garcia-Saez, I., Couté, Y., Yamaryo-Botté, Y., Boeri Erba, E., Adrait, A., ... & Khochbin, S. (2023). Nucleoside diphosphate kinases 1 and 2 regulate a protective liver response to a high-fat diet. Science Advances, 9(36), eadh0140.

Adam, K., Lesperance, J., Hunter, T., & Zage, P. E. (2020). The potential functional roles of NME1 histidine kinase activity in neuroblastoma pathogenesis. International journal of molecular sciences, 21(9), 3319.

Adam, K., Ning, J., Reina, J., & Hunter, T. (2020). NME/NM23/NDPK and histidine phosphorylation. International journal of molecular sciences, 21(16), 5848.

Mátyási, B., Farkas, Z., Kopper, L., Sebestyén, A., Boissan, M., Mehta, A., & Takács-Vellai, K. (2020). The function of NM23-H1/NME1 and its homologs in major processes linked to metastasis. Pathology & Oncology Research, 26, 49-61.

Radić, M., Šoštar, M., Weber, I., Ćetković, H., Slade, N., & Herak Bosnar, M. (2020). The subcellular localization and oligomerization preferences of NME1/NME2 upon radiation-induced DNA damage. International Journal of Molecular Sciences, 21(7), 2363.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

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Mouse Anti-NME1 Recombinant Antibody (6E8)

Mouse Anti-NME1 Recombinant Antibody (CBWJN-0079)

Mouse Anti-NME1 Recombinant Antibody (7F4)

Mouse Anti-NME1 Recombinant Antibody (1D12)

Mouse Anti-NME1 Recombinant Antibody (1C11)

Mouse Anti-NME1 Recombinant Antibody (7A1)

Mouse Anti-NME1 Recombinant Antibody (7E5)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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