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MMP1 Matched Antibody Pair (740) (APMAB-740LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-MMP1 monoclonal, IgG2a antibody, 100 ug
Detection Antibody
Anti-MMP1 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Alternative Names
Matrix Metallopeptidase 1; Interstitial Collagenase; Fibroblast Collagenase; EC 3.4.24.7; CLG; Matrix Metalloproteinase 1 (Interstitial Collagenase); Matrix Metallopeptidase 1 (Interstitial Collagenase);
Entrez Gene ID
4312
UniProt ID
P03956
More Infomation

Bartold, K., Iskierko, Z., Borowicz, P., Noworyta, K., Lin, C. Y., Kalecki, J., ... & Kutner, W. (2022). Molecularly imprinted polymer-based extended-gate field-effect transistor (EG-FET) chemosensor for selective determination of matrix metalloproteinase-1 (MMP-1) protein. Biosensors and Bioelectronics, 208, 114203.

Alwan, I. T., & Ghali, K. H. (2021). Association Risk of Metalomatrix Proteinase Enzymes Levels (MMP-1, MMP-9 And MMP-13) with Development of Rheumatoid Arthritis. Annals of the Romanian Society for Cell Biology, 11369-11378.

Cárcel-Márquez, J., Cullell, N., Muiño, E., Gallego-Fabrega, C., Lledós, M., Ibañez, L., ... & Fernandez-Cadenas, I. (2021). Causal effect of MMP-1 (matrix metalloproteinase-1), MMP-8, and MMP-12 levels on ischemic stroke: a Mendelian randomization study.

Wang, M., Zhou, Y., Huang, W., Zeng, Y., & Li, X. (2020). Association between matrix metalloproteinase-1 (MMP-1) protein level and the risk of rheumatoid arthritis and osteoarthritis: a meta-analysis. Brazilian Journal of Medical and Biological Research, 54, e10366.

Balkhi, S., Mashayekhi, F., Salehzadeh, A., & Saedi, H. S. (2020). Matrix metalloproteinase (MMP)-1 and MMP-3 gene variations affect MMP-1 and-3 serum concentration and associates with breast cancer. Molecular Biology Reports, 47(12), 9637-9644.

Mohammadian, H., Sharifi, R., Amirdehi, S. R., Taheri, E., & Bedoustani, A. B. (2020). Matrix metalloproteinase MMP1 and MMP9 genes expression in breast cancer tissue. Gene Reports, 21, 100906.

Zamolo, G., Grahovac, M., Žauhar, G., Vučinić, D., Kovač, L., Brajenić, N., & Grahovac, B. (2020). Matrix metalloproteinases MMP‐1, MMP‐2, and MMP‐13 are overexpressed in primary nodular melanoma. Journal of cutaneous pathology, 47(2), 139-145.

Chang, Y. T., Chu, L. J., Liu, Y. C., Chen, C. J., Wu, S. F., Chen, C. H., ... & Yu, J. S. (2020). Verification of saliva matrix metalloproteinase-1 as a strong diagnostic marker of oral cavity cancer. Cancers, 12(8), 2273.

Szóstek-Mioduchowska, A., Słowińska, M., Pacewicz, J., Skarzynski, D. J., & Okuda, K. (2020). Matrix metallopeptidase expression and modulation by transforming growth factor-β1 in equine endometrosis. Scientific Reports, 10(1), 1119.

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For research use only. Not intended for any clinical use.

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