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MAGED1 Matched Antibody Pair (709) (APMAB-709LY)

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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-MAGED1 polyclonal antibody, 100 ug
Detection Antibody
Anti-MAGED1 Mouse monoclonal, IgG2b antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alternative Names
MAGE Family Member D1; Neurotrophin Receptor-Interacting MAGE Homolog; Melanoma Antigen Family D1; MAGE Tumor Antigen CCF; MAGE-D1 Antigen; NRAGE; Melanoma-Associated Antigen D1; Melanoma Antigen Family D, 1; DLXIN-1;
Entrez Gene ID
UniProt ID
More Infomation

Cheron, J., Beccari, L., Hagué, P., Icick, R., Despontin, C., Carusone, T., ... & de Kerchove d’Exaerde, A. (2023). USP7/Maged1-mediated H2A monoubiquitination in the paraventricular thalamus: an epigenetic mechanism involved in cocaine use disorder. Nature communications, 14(1), 8481.

Wang, J., Xu, S. Y., Ye, Z. Y., Sun, Z. N., Zhang, J. Q., Qi, C., ... & Gao, J. (2023). The deficiency of Maged1 attenuates Parkinson's disease progression in mice. Molecular Brain, 16(1), 1-16.

Park, S., Kwon, W., Kim, H. Y., Ji, Y. R., Kim, D., Kim, W., ... & Choi, S. K. (2022). Knockdown of Maged1 inhibits cell cycle progression and causes cell death in mouse embryonic stem cells. Differentiation, 125, 18-26.

Cheron, J., Beccari, L., Hagué, P., Icick, R., Despontin, C., Carusone, T., ... & de Kerchove d’Exaerde, A. (2022). USP7/Maged1-Mediated H2A Monoubiquitination in the Paraventricular Thalamus: An Epigenetic Mechanism Involved in Cocaine Use Disorder. bioRxiv, 2022-11.

Hu, L., Wang, J., Huang, H., Yu, Y., Ding, J., Yu, Y., ... & Chen, F. (2021). YTHDF1 regulates pulmonary hypertension through translational control of MAGED1. American journal of respiratory and critical care medicine, 203(9), 1158-1172.

Zhang, B., Li, D., Jin, X., & Zhang, K. (2020). The CDK4/6 inhibitor PD0332991 stabilizes FBP1 by repressing MAGED1 expression in pancreatic ductal adenocarcinoma. The International Journal of Biochemistry & Cell Biology, 128, 105859.

Wang, J., You, W. Y., Ye, Q., Zhang, J. Q., He, C., Qi, C., ... & Gao, J. (2020). The Deficiency of Maged1 Attenuates Parkinson's Disease Progression by Inhibiting Apoptosis and Enhancing Autophagy in Mice.

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For research use only. Not intended for any clinical use.

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