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KIF2C Matched Antibody Pair (664) (APMAB-664LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-KIF2C monoclonal antibody, 100 ug
Detection Antibody
Anti-KIF2C Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a kinesin-like protein that functions as a microtubule-dependent molecular motor. The encoded protein can depolymerize microtubules at the plus end, thereby promoting mitotic chromosome segregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Alternative Names
Kinesin Family Member 2C; Mitotic Centromere-Associated Kinesin; Kinesin-Like Protein 6; KNSL6; MCAK; Kinesin-Like 6 (Mitotic Centromere-Associated Kinesin); Testis Tissue Sperm-Binding Protein Li 68n; Kinesin-Like Protein KIF2C; CT139;
Entrez Gene ID
11004
UniProt ID
Q99661
More Infomation

Li, S., Ma, Y., Wu, C., & Hou, X. (2023). Knockdown of kinesin family member 2C restricts cell proliferation and induces cell cycle arrest in gastric cancer.

Zhang, B., Li, Y., Pang, X., & Wu, H. (2022). Bioinformatics analysis of kinesin family member 2C in human tumors: novel prognostic biomarker and tumor microenvironment regulator.

Yang, J., Wu, Z., Yang, L., Jeong, J. H., Zhu, Y., Lu, J., ... & Li, R. (2022). Characterization of kinesin family member 2C as a proto-oncogene in cervical cancer. Frontiers in Pharmacology, 12, 785981.

Zhang, B., Liu, P., Li, Y., Hu, Q., Li, H., Pang, X., & Wu, H. (2022). Multi-omics analysis of kinesin family member 2C in human tumors: novel prognostic biomarker and tumor microenvironment regulator. American Journal of Cancer Research, 12(11), 4954.

Mo, S., Fang, D., Zhao, S., Hoa, P. T. T., Zhou, C., Liang, T., ... & Han, C. (2022). Down regulated oncogene KIF2C inhibits growth, invasion, and metastasis of hepatocellular carcinoma through the Ras/MAPK signaling pathway and epithelial-to-mesenchymal transition. Annals of Translational Medicine, 10(3).

Ding, Q., Jiang, C., Zhou, Y., Duan, J., Lai, J., Jiang, M., & Lin, D. (2021). Kinesin family member 2C promotes hepatocellular carcinoma growth and metastasis via activating MEK/ERK pathway. Bioscience, Biotechnology, and Biochemistry, 85(11), 2241-2249.

Li, X., Huang, W., Huang, W., Wei, T., Zhu, W., Chen, G., & Zhang, J. (2020). Kinesin family members KIF2C/4A/10/11/14/18B/20A/23 predict poor prognosis and promote cell proliferation in hepatocellular carcinoma. American Journal of Translational Research, 12(5), 1614.

Zhu, S., Paydar, M., Wang, F., Li, Y., Wang, L., Barrette, B., ... & Peng, A. (2020). Kinesin Kif2C in regulation of DNA double strand break dynamics and repair. Elife, 9, e53402.

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For research use only. Not intended for any clinical use.

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