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GAD2 Matched Antibody Pair (460) (APMAB-460LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-GAD2 monoclonal, IgG2a antibody, 100 ug
Detection Antibody
Anti-GAD2 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2008]
Alternative Names
Glutamate Decarboxylase 2; Glutamate Decarboxylase 2 (Pancreatic Islets And Brain, 65kDa); Glutamate Decarboxylase 65 KDa Isoform; 5 KDa Glutamic Acid Decarboxylase; EC 4.1.1.15; GAD-65;
Entrez Gene ID
2572
UniProt ID
Q05329
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For research use only. Not intended for any clinical use.

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