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FGF21 Matched Antibody Pair (437) (APMAB-437LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-FGF21 polyclonal antibody, 100 ug
Detection Antibody
Anti-FGF21 Mouse monoclonal, IgG1 antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
Theis gene encodes a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes. This protein is a secreted endocrine factor that functions as a major metabolic regulator. The encoded protein stimulates the uptake of glucose in adipose tissue. [provided by RefSeq, Mar 2016]
Alternative Names
Fibroblast Growth Factor 21; FGF-21;
Entrez Gene ID
26291
UniProt ID
Q9NSA1
More Infomation

Sommakia, S., Almaw, N. H., Lee, S. H., Ramadurai, D. K., Taleb, I., Kyriakopoulos, C. P., ... & Chaudhuri, D. (2022). FGF21 (Fibroblast Growth Factor 21) defines a potential cardiohepatic signaling circuit in end-stage heart failure. Circulation: Heart Failure, 15(3), e008910.

Lu, H., Jia, C., Wu, D., Jin, H., Lin, Z., Pan, J., ... & Wang, W. (2021). Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling pathway. Cell death & disease, 12(10), 1-13.

Janzi, S., González-Padilla, E., Najafi, K., Ramne, S., Ahlqvist, E., Borné, Y., & Sonestedt, E. (2021). Single Nucleotide Polymorphisms in Close Proximity to the Fibroblast Growth Factor 21 (FGF21) Gene Found to Be Associated with Sugar Intake in a Swedish Population. Nutrients, 13(11), 3954.

Wu, L., Qian, L., Zhang, L., Zhang, J., Zhou, J., Li, Y., ... & Jia, W. (2020). Fibroblast growth factor 21 is related to atherosclerosis independent of nonalcoholic fatty liver disease and predicts atherosclerotic cardiovascular events. Journal of the American Heart Association, 9(11), e015226.

Forsström, S., Jackson, C. B., Carroll, C. J., Kuronen, M., Pirinen, E., Pradhan, S., ... & Suomalainen, A. (2019). Fibroblast growth factor 21 drives dynamics of local and systemic stress responses in mitochondrial myopathy with mtDNA deletions. Cell metabolism, 30(6), 1040-1054.

Tucker, B., Li, H., Long, X., Rye, K. A., & Ong, K. L. (2019). Fibroblast growth factor 21 in non-alcoholic fatty liver disease. Metabolism, 101, 153994.

Martínez-Garza, Ú., Torres-Oteros, D., Yarritu-Gallego, A., Marrero, P. F., Haro, D., & Relat, J. (2019). Fibroblast growth factor 21 and the adaptive response to nutritional challenges. International journal of molecular sciences, 20(19), 4692.

Su, X., Kong, Y., & Peng, D. (2019). Fibroblast growth factor 21 in lipid metabolism and non-alcoholic fatty liver disease. Clinica Chimica Acta, 498, 30-37.

Shi, Y., Wang, S., Peng, H., Lv, Y., Li, W., Cheng, S., & Liu, J. (2019). Fibroblast growth factor 21 attenuates vascular calcification by alleviating endoplasmic reticulum stress mediated apoptosis in rats. International journal of biological sciences, 15(1), 138.

Gao, R. Y., Hsu, B. G., Wu, D. A., Hou, J. S., & Chen, M. C. (2019). Serum fibroblast growth factor 21 levels are positively associated with metabolic syndrome in patients with type 2 diabetes. International journal of endocrinology, 2019.

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For research use only. Not intended for any clinical use.

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