CHN1 Matched Antibody Pair (270) (APMAB-270LY)

Name: CHN1 Matched Antibody Pair (270)
SKU: APMAB-270LY
Rating: 5 (1 reviews)

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Datasheet

Specifications

ApplIcation

Sandwich ELISA

Specificity

Human

Capture Antibody

Rabbit anti-CHN1 polyclonal antibody, 100 ug

Detection Antibody

Anti-CHN1 Mouse polyclonal antibody, 40 ul

Dilutions

10 ng/ml-100 ng/ml

Format

Liquid

Storage

Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.

Introduction

This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]

Alternative Names

Chimerin 1; Rho GTPase-Activating Protein 2; Chimerin (Chimaerin) 1; Alpha-Chimerin; Chimaerin 1; A-Chimaerin; N-Chimerin; ARHGAP2; CHN;

Entrez Gene ID

1123

UniProt ID

P15882

More Infomation

References

Li, J. P., Zeng, S. H., Zhang, Y. H., & Liu, Y. J. (2021). Bioinformatics-based analysis of the association between the A1-chimaerin (CHN1) gene and gastric cancer. Bioengineered, 12(1), 2874-2889.

Zhao, H., Wang, L., Wang, S., Chen, X., Liang, M., Zhang, X., ... & Xu, X. (2021). CHN1 promotes epithelial–mesenchymal transition via the Akt/GSK-3β/Snail pathway in cervical carcinoma. Journal of Translational Medicine, 19(1), 1-12.

Zhou, T. C., Duan, W. H., Fu, X. L., Zhu, Q., Guo, L. Y., Zhou, Y., ... & Hu, M. (2020). Identification of a novel CHN1 p.(Phe213Val) variant in a large Han Chinese family with congenital Duane retraction syndrome. Scientific reports, 10(1), 1-9.

Liu, J., Li, Y., Chen, X., Xu, X., Zhao, H., Wang, S., ... & Wang, J. (2020). Upregulation of miR-205 induces CHN1 expression, which is associated with the aggressive behaviour of cervical cancer cells and correlated with lymph node metastasis. BMC cancer, 20(1), 1-13.

Biler, E. D., Ilim, O., Onay, H., & Uretmen, O. (2017). CHN1 gene mutation analysis in patients with Duane retraction syndrome. Journal of American Association for Pediatric Ophthalmology and Strabismus, 21(6), 472-475.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-CHN1 Recombinant Antibody (3A3)

Mouse Anti-CHN1 Recombinant Antibody (4D1)

Mouse Anti-CHN1 Recombinant Antibody (3F8)

Mouse Anti-CHN1 Recombinant Antibody (2A1)

Mouse Anti-CHN1 Recombinant Antibody (CBFYC-1843)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
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Second antibody and isotype control

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