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CD248 Matched Antibody Pair (212) (APMAB-212LY)

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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-CD248 polyclonal antibody, 100 ug
Detection Antibody
Anti-CD248 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
CD248 (CD248 Molecule) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include calcium ion binding and extracellular matrix binding. An important paralog of this gene is CD93.
Alternative Names
CD248 Molecule; Tumor Endothelial Marker 1; CD248 Molecule, Endosialin; CD248 Antigen, Endosialin; CD164 Sialomucin-Like 1; Endosialin;
Entrez Gene ID
UniProt ID
More Infomation

Zhang, K., Xu, C., Liu, S., Jiang, Y., Zhao, X., Ma, S., ... & Qin, W. (2021). The Diagnostic and Immunotherapeutic Value of CD248 in Renal Cell Carcinoma. Frontiers in oncology, 11, 510.

Armitage, E. G., Barnes, A., Patrick, K., Bechar, J., Harrison, M. J., Lavery, G. G., ... & Naylor, A. J. (2021). Metabolic consequences for mice lacking Endosialin: LC–MS/MS-based metabolic phenotyping of serum from C56Bl/6J Control and CD248 knock‐out mice. Metabolomics, 17(2), 1-11.

Matsushima, S., Aoshima, Y., Akamatsu, T., Enomoto, Y., Meguro, S., Kosugi, I., ... & Iwashita, T. (2020). CD248 and integrin alpha-8 are candidate markers for differentiating lung fibroblast subtypes. BMC pulmonary medicine, 20(1), 1-15.

Park, G. B., Jeong, J. Y., & Kim, D. (2020). Modified TLR‐mediated downregulation of miR‐125b‐5p enhances CD248 (endosialin)‐induced metastasis and drug resistance in colorectal cancer cells. Molecular carcinogenesis, 59(2), 154-167.

Di Benedetto, P., Ruscitti, P., Liakouli, V., Del Galdo, F., Giacomelli, R., & Cipriani, P. (2019). Linking myofibroblast generation and microvascular alteration: the role of CD248 from pathogenesis to therapeutic target. Molecular medicine reports, 20(2), 1488-1498.

Teicher, B. A. (2019). CD248: A therapeutic target in cancer and fibrotic diseases. Oncotarget, 10(9), 993.

Petrus, P., Fernandez, T. L., Kwon, M. M., Huang, J. L., Lei, V., Safikhan, N. S., ... & Conway, E. M. (2019). Specific loss of adipocyte CD248 improves metabolic health via reduced white adipose tissue hypoxia, fibrosis and inflammation. EBioMedicine, 44, 489-501.

Di Benedetto, P., Liakouli, V., Ruscitti, P., Berardicurti, O., Carubbi, F., Panzera, N., ... & Giacomelli, R. (2018). Blocking CD248 molecules in perivascular stromal cells of patients with systemic sclerosis strongly inhibits their differentiation toward myofibroblasts and proliferation: a new potential target for antifibrotic therapy. Arthritis research & therapy, 20(1), 1-12.

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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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