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B4GALT4 Matched Antibody Pair (122) (APMAB-122LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-B4GALT4 monoclonal antibody, 100 ug
Detection Antibody
Anti-B4GALT4 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis. [provided by RefSeq, Jul 2008]
Alternative Names
Beta-1,3-Galactosyltransferase 4; Ganglioside Galactosyltransferase; UDP-Galactose:Beta-N-Acetyl-Galactosamine-Beta-1,3-Galactosyltransferase; UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase, Polypeptide 4; UDP-Gal:BetaGlcNAc Beta 1,3-Galactosyltransferase 4; Beta-1,3-GalTase 4; EC 2.4.1.62; BETA3GALT4;
Entrez Gene ID
8702
UniProt ID
O96024
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For research use only. Not intended for any clinical use.

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