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Mouse Anti-ZFP42 Recombinant Antibody (5E11A6) (CBMAB-Z0231-WJ)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
5E11A6
Antibody Isotype
IgG1, κ
Application
ELISA, FC, IHC, IHC-P, WB

Basic Information

Immunogen
The immunogen corresponding to a region within AA249-310 of human ZFP42 expressed in E. Coli.
Specificity
Human, Mouse
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL

Target

Full Name
ZFP42 Zinc Finger Protein
Introduction
ZFP42 (ZFP42 Zinc Finger Protein) is a Protein Coding gene. Diseases associated with ZFP42 include Mixed Germ Cell Cancer. Among its related pathways are Cardiac Progenitor Differentiation and Preimplantation Embryo. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is YY1.
Entrez Gene ID
Human132625
Mouse22702
UniProt ID
HumanQ96MM3
MouseP22227
Alternative Names
ZFP42 Zinc Finger Protein; Reduced Expression Protein 1; Zinc Finger Protein 754; Zfp-42; ZNF754; REX-1; REX1
Function
Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal (By similarity).
Biological Process
Biological Process female gonad development Source:UniProtKB1 Publication
Biological Process male gonad development Source:UniProtKB1 Publication
Biological Process meiotic cell cycle Source:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Nucleus
PTM
Polyubiquitinated by RNF12, leading to proteasomal degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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