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Rabbit Anti-ZFP42 Recombinant Antibody (14H16L9) (CBMAB-R4097-CN)


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Summary

Host Animal
Rabbit
Specificity
Dog, Human
Clone
14H16L9
Antibody Isotype
IgG
Application
ICC, IF, WB

Basic Information

Immunogen
Recombinant protein corresponding to aa. 1-140 of human REX1 transcription factor
Specificity
Dog, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS
Preservative
0.09% Sodium azide
Concentration
0.5 mg/mL

Target

Full Name
ZFP42 Zinc Finger Protein
Introduction
Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal (By similarity).
Entrez Gene ID
Human132625
Dog100856057
UniProt ID
HumanQ96MM3
DogA0A8I3P1G1
Alternative Names
REX1; REX-1; ZNF754; zfp-42REX1; REX-1; ZNF754; zfp-42
Function
Involved in the reprogramming of X-chromosome inactivation during the acquisition of pluripotency. Required for efficient elongation of TSIX, a non-coding RNA antisense to XIST. Binds DXPas34 enhancer within the TSIX promoter. Involved in ES cell self-renewal (By similarity).
Biological Process
Biological Process female gonad development Source:UniProtKB1 Publication
Biological Process male gonad development Source:UniProtKB1 Publication
Biological Process meiotic cell cycle Source:UniProtKB1 Publication
Biological Process regulation of transcription by RNA polymerase II Source:GO_Central1 Publication
Cellular Location
Nucleus
PTM
Polyubiquitinated by RNF12, leading to proteasomal degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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