Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-UCKL1 Recombinant Antibody (B-11) (CBMAB-C4486-CN)


See all UCKL1 antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
B-11
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 31-142 mapping near the N-terminus of UCKL1 of human origin
Specificity
Human, Mouse, Rat
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Target

Full Name
uridine-cytidine kinase 1-like 1
Introduction
The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Entrez Gene ID
Human54963
Mouse68556
Rat499956
UniProt ID
HumanQ9NWZ5
MouseQ91YL3
RatD3ZYQ8
Alternative Names
Uridine-Cytidine Kinase 1 Like 1; EC 2.7.1.48; URKL1; Uridine-Cytidine Kinase 1-Like 1; Uridine-Cytidine Kinase-Like 1; Uridine Kinase-Like 1; UCK1-LIKE; UCK1L;
Function
May contribute to UTP accumulation needed for blast transformation and proliferation.
Biological Process
Biological Process CTP salvage Source:UniProtKB-UniPathway
Biological Process phosphorylation Source:UniProtKB-KW
Biological Process pyrimidine nucleoside salvage Source:Reactome
Biological Process UMP salvage Source:UniProtKB-UniPathway
Cellular Location
Cytoplasm
Nucleus
EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.
PTM
Ubiquitinated by RNF19B; which induces proteasomal degradation.
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-UCKL1 Recombinant Antibody (B-11)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quoteOnline Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry