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Mouse Anti-UCKL1 Monoclonal Antibody (8D4) (CBMAB-1686-YC)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
8D4
Antibody Isotype
IgG1, κ
Application
ELISA, ICC, IF, WB

Basic Information

Immunogen
Partial recombinant protein UCKL1 (NP_060329, aa 301- 401) with GST tag.
Specificity
Human, Mouse
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
uridine-cytidine kinase 1-like 1
Introduction
UCKL1 may contribute to UTP accumulation needed for blast transformation and proliferation.
Entrez Gene ID
Human54963
Mouse68556
UniProt ID
HumanQ9NWZ5
MouseQ91YL3
Alternative Names
RGD1565465
Function
May contribute to UTP accumulation needed for blast transformation and proliferation.
Biological Process
Biological Process CTP salvage Source:UniProtKB-UniPathway
Biological Process phosphorylation Source:UniProtKB-KW
Biological Process pyrimidine nucleoside salvage Source:Reactome
Biological Process UMP salvage Source:UniProtKB-UniPathway
Cellular Location
Cytoplasm
Nucleus
EBNA3 induces isoform 1 translocation to the nucleus, whereas it does change isoform 3 location.
PTM
Ubiquitinated by RNF19B; which induces proteasomal degradation.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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