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Mouse Anti-TSPAN8 Recombinant Antibody (CBYJT-5085) (CBMAB-T4663-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-5085
Antibody Isotype
IgG3
Application
WB, IP, IF, IHC(P), ELISA

Basic Information

Immunogen
Raised against amino acids of 110-205 of TSPAN8 of human origin
Specificity
Human
Antibody Isotype
IgG3
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.1 mg/mL
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Tetraspanin 8
Introduction
TSPAN8 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. It mediate signal transduction events that function in the regulation of cell development, activation, growth and motility. TSPAN8 is a cell surface glycoprotein that is known to complex with integrins. TSPAN8 is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene.
Entrez Gene ID
7103
UniProt ID
P19075
Alternative Names
Tetraspanin 8; Transmembrane 4 Superfamily Member 3; Tumor-Associated Antigen CO-029; Tspan-8; TM4SF3; Tetraspanin-8; CO-029
Biological Process
Biological Process negative regulation of blood coagulation Source:Ensembl
Biological Process regulation of gene expression Source:Ensembl
Biological Process spermatogenesis Source:Ensembl
Cellular Location
Membrane
Topology
Cytoplasmic: 1-9
Helical: 10-33
Extracellular: 34-57
Helical: 58-72
Cytoplasmic: 73-83
Helical: 84-109
Extracellular: 110-205
Helical: 206-230
Cytoplasmic: 231-237
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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