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Mouse Anti-TNS4 Recombinant Antibody (CBYJT-4130) (CBMAB-T3574-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-4130
Antibody Isotype
IgG1
Application
WB, IHC

Basic Information

Immunogen
E. coli-derived recombinant human Tensin 4/CTEN, Ser2-Gln107, Accession # Q8IZW8
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 2-107

Target

Full Name
TNS4
Introduction
TNS4 (Tensin 4) is a Protein Coding gene. Diseases related to TNS4 include Colorectal Cancer. Among its related pathways are MET promotes cell motility and Signaling by GPCR. Gene Ontology (GO) annotations related to TNS4 include actin binding. An important paralog of TNS4 is TNS1.
Entrez Gene ID
84951
UniProt ID
Q8IZW8
Alternative Names
Tensin 4; C-Terminal Tensin-Like Protein; C Terminal Tensin Like; CTEN; Tensin-4; PP14434
Function
May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity).
May promote apoptosis, via its cleavage by caspase-3.
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process protein localization Source:UniProtKB1 Publication
Cellular Location
Cell junction, focal adhesion
Cytoplasm, cytoskeleton
PTM
Proteolytically cleaved by caspase-3 during apoptosis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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