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Mouse Anti-TNS4 Antibody (13F4) (CBMAB-1679CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
13F4
Antibody Isotype
IgG2a
Application
ELISA, MA

Basic Information

Immunogen
Recombinant protein (aa 436-574; SH2 domain)
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TNS4
Introduction
TNS4 (Tensin 4) may be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton. It can promote apoptosis, via its cleavage by caspase-3. Diseases associated with TNS4 include Colorectal Cancer. Among its related pathways are MET promotes cell motility and Signaling by GPCR. GO annotations related to this gene include actin binding.
Entrez Gene ID
84951
UniProt ID
Q8IZW8
Alternative Names
CTEN; PP14434
Function
May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity).
May promote apoptosis, via its cleavage by caspase-3.
Biological Process
Biological Process apoptotic process Source:UniProtKB-KW
Biological Process protein localization Source:UniProtKB1 Publication
Cellular Location
Cell junction, focal adhesion
Cytoplasm, cytoskeleton
PTM
Proteolytically cleaved by caspase-3 during apoptosis.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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