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Armenian Hamster Anti-Tmpo Recombinant Antibody (RL29) (CBMAB-L2718-YJ)

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Summary

Host Animal
Armenian Hamster
Specificity
Rat
Clone
RL29
Antibody Isotype
IgG
Application
WB, IP, ICC, IF

Basic Information

Specificity
Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Thymopoietin
Introduction
Tmpo binds to both lamin B1 and chromosomes in a mitotic phosphorylation-regulated manner.
Entrez Gene ID
UniProt ID
Alternative Names
LAP2; lamina-associated polypeptide 2, isoform beta; lamina-associated polypeptide 2; TP beta; Thymopoietin (lamina associated polypeptide 2); thymopoietin isoform beta
Function
May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together with LMNA, in the nuclear anchorage of RB1.
TP and TP5 may play a role in T-cell development and function. TP5 is an immunomodulating pentapeptide.
Cellular Location
Nucleus
Chromosome
Expressed diffusely throughout the nucleus.
PTM
Phosphorylated in a mitose-specific manner.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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