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Mouse Anti-SMNDC1 (AA 1-239) Recombinant Antibody (CBXS-0565) (CBMAB-S3507-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-0565
Antibody Isotype
IgG1
Application
ELISA, IHC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.2
Preservative
0.09% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-239

Target

Full Name
SMNDC1
Introduction
This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene.
Entrez Gene ID
10285
UniProt ID
O75940
Alternative Names
Survival Motor Neuron Domain Containing 1; Splicing Factor 30, Survival Of Motor Neuron-Related; Survival Motor Neuron Domain-Containing Protein 1; 30 KDa Splicing Factor SMNrp; Tudor Domain Containing 16C; SMN-Related Protein;
Function
Involved in spliceosome assembly.
Biological Process
Biological Process apoptotic processManual Assertion Based On ExperimentTAS:ProtInc
Biological Process mRNA processingIEA:UniProtKB-KW
Biological Process RNA splicing, via transesterification reactionsManual Assertion Based On ExperimentTAS:UniProtKB
Cellular Location
Nucleus speckle
Nucleus, Cajal body
Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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