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Rat Anti-SEZ6L2 Recombinant Antibody (CBYC-P834) (CBMAB-P3663-YC)


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Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYC-P834
Antibody Isotype
IgG2a
Application
IHC, WB

Basic Information

Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS with 5% trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 28-837

Target

Full Name
seizure related 6 homolog like 2
Introduction
SEZ6L2 is a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer.
Entrez Gene ID
233878
UniProt ID
Q4V9Z5
Alternative Names
Seizure Related 6 Homolog Like 2; Type I Transmembrane Receptor (Seizure Related Protein); Type I Transmembrane Receptor (Seizure-Related Protein); Seizure Related 6 Homolog (Mouse)-Like 2; Seizure Related 6-Like Protein 2; Seizure 6-Like Protein 2; BSRPA; PSK-1; PSK;
Function
May contribute to specialized endoplasmic reticulum functions in neurons.
Biological Process
Biological Process regulation of protein kinase C signalingManual Assertion Based On ExperimentIBA:GO_Central
Biological Process synapse maturationManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cell membrane
Endoplasmic reticulum membrane
Detected on cell surface of lung-cancer.
Topology
Extracellular: 28-844
Helical: 845-865
Cytoplasmic: 866-910
PTM
O-glycosylated with core 1 or possibly core 8 glycans.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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