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Rat Anti-SELENOP Recombinant Antibody (9S4) (CBMAB-0329-CN)


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Summary

Host Animal
Rat
Specificity
Mouse
Clone
9S4
Antibody Isotype
IgG1, κ
Application
ELISA, IF, IP, WB

Basic Information

Immunogen
Polypeptide
Specificity
Mouse
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Selenop
Introduction
This gene encodes a selenoprotein that is predominantly expressed in the liver and secreted into the plasma. This selenoprotein is unique in that it contains multiple selenocysteine (Sec) residues per polypeptide (10 in mouse), and accounts for most of the selenium in plasma. It has been implicated as an extracellular antioxidant, and in the transport of selenium to extra-hepatic tissues via apolipoprotein E receptor-2 (apoER2). The protein might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium.
Entrez Gene ID
20363
UniProt ID
P70274
Alternative Names
Se-P; selp; Sepp1; AU018766; D15Ucla1
Function
Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.
Biological Process
Biological Process brain developmentIEA:Ensembl
Biological Process locomotory behaviorIEA:Ensembl
Biological Process post-embryonic developmentIEA:Ensembl
Biological Process regulation of growthIEA:Ensembl
Biological Process response to oxidative stressManual Assertion Based On ExperimentTAS:ProtInc
Biological Process response to selenium ionIEA:Ensembl
Biological Process selenium compound metabolic processManual Assertion Based On ExperimentIBA:GO_Central
Biological Process sexual reproductionIEA:Ensembl
Cellular Location
Secreted
Passes from plasma into the glomerular filtrate where it is removed by endocytosis mediated by LRP2 in the proximal tubule epithelium.
PTM
Phosphorylation sites are present in the extracellular medium.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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