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Mouse Anti-PYY Recombinant Antibody (RPY-B12) (CBMAB-P3584-YC)


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Summary

Host Animal
Mouse
Specificity
Rat
Clone
RPY-B12
Antibody Isotype
IgG1
Application
WB, ELISA, ICC, IF

Basic Information

Immunogen
Synthetic peptide (full length, 34 amino acids)
Specificity
Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
peptide YY
Introduction
PYY is a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis.
Entrez Gene ID
287730
UniProt ID
P10631
Alternative Names
PYY-I; PYY1
Function
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
Biological Process
Biological Process feeding behaviorManual Assertion Based On ExperimentIBA:GO_Central
Biological Process intestinal epithelial cell differentiationManual Assertion Based On ExperimentTAS:GO_Central
Biological Process neuropeptide signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Secreted
PTM
The peptide YY form is cleaved at Pro-30 by the prolyl endopeptidase FAP (seprase) activity (in vitro) to generate peptide YY(3-36).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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