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Mouse Anti-PPY Recombinant Antibody (327) (CBMAB-P2672-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
327
Antibody Isotype
IgG2a
Application
WB

Basic Information

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Pancreatic Polypeptide.
Specificity
Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
pancreatic polypeptide
Introduction
PPY is a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa.
Entrez Gene ID
5539
UniProt ID
P01298
Alternative Names
PNP; PP
Function
Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.
The physiological role for the icosapeptide has not yet been elucidated.
Biological Process
Feeding behaviorManual Assertion Based On ExperimentIBA:GO_Central
Neuropeptide signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Protein secretionManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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