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Mouse Anti-p53 Antibody (H1) (CBMAB-1479CQ)


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Summary

Host Animal
Mouse
Specificity
Common fruit fly
Clone
H1
Antibody Isotype
IgG2a
Application
ELISA, IP

Basic Information

Immunogen
Recombinant GST fusion protein of Drosophila p53
Specificity
Common fruit fly
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
p53
Introduction
Dmp53 shares significant amino acid identity with the DNA-binding domain of p53, including conservation of key residues commonly mutated in human cancer. Like p53, overexpression of Dmp53 induces apoptosis, and inhibition of Dmp53 function renders cells resistant to X ray–induced apoptosis. In contrast to mammalian p53, Dmp53 overexpression does not induce a G1 cell cycle block, and inhibition of Dmp53 activity does not affect X ray–induced cell cycle arrest.
Entrez Gene ID
2768677
UniProt ID
Q9N6D8
Alternative Names
CG10873; CG31325; CG33336; D-p53; Dm-P53; Dmel\CG33336; dmp53; Dmp53; DmP53; DMP53; dp53; Dp53; prac
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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