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Rabbit Anti-MSI1 Monoclonal Antibody (EP1302) (CBMAB-1399-YC)


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Summary

Host Animal
Rabbit
Specificity
Human, Chicken
Clone
EP1302
Antibody Isotype
IgG
Application
FC, ICC, IF, IHC-Fr, IHC-P, IP, WB

Basic Information

Immunogen
Corresponding to Human Musashi 1/ Msi1 (N terminal).
Specificity
Human, Chicken
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Musashi RNA Binding Protein 1
Introduction
MSI1 is a protein containing two conserved tandem RNA recognition motifs. Expression of MSI1 has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas.
Entrez Gene ID
Human4440
Chicken416979
UniProt ID
HumanO43347
ChickenF1NSZ7
Alternative Names
musashi-1; musashi1
Function
RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U1-3AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Biological Process
Epithelial cell differentiation Source: Ensembl
Nervous system development Source: ProtInc
Response to hormone Source: Ensembl
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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