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Mouse Anti-MSI1 Recombinant Antibody (A1190) (CBMAB-AP12299LY)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
A1190
Antibody Isotype
IgG
Application
WB

Basic Information

Immunogen
Recombinant full length Human Musashi-1
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
Affinity purity
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Musashi RNA Binding Protein 1
Introduction
This gene encodes a protein containing two conserved tandem RNA recognition motifs. Similar proteins in other species function as RNA-binding proteins and play central roles in posttranscriptional gene regulation. Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas. A pseudogene for this gene is located on chromosome 11q13. [provided by RefSeq, Jul 2008]
Entrez Gene ID
Human4440
Mouse17690
Rat259272
UniProt ID
HumanO43347
MouseQ61474
RatQ8K3P4
Alternative Names
Musashi RNA Binding Protein 1; Musashi-1; RNA-Binding Protein Musashi Homolog 1; Musashi (Drosophila) Homolog 1; Musashi Homolog 1 (Drosophila); Musashi1;
Function
RNA binding protein that regulates the expression of target mRNAs at the translation level. Regulates expression of the NOTCH1 antagonist NUMB. Binds RNA containing the sequence 5'-GUUAGUUAGUUAGUU-3' and other sequences containing the pattern 5'-[GA]U1-3AGU-3'. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Biological Process
Epithelial cell differentiation Source: Ensembl
Nervous system development Source: ProtInc
Response to hormone Source: Ensembl
Cellular Location
Cytoplasm
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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