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Mouse Anti-LY75 Recombinant Antibody (CBYJL-2212) (CBMAB-L2450-YJ)


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Summary

Host Animal
Mouse
Specificity
Human, Rat
Clone
CBYJL-2212
Antibody Isotype
IgG1
Application
WB, IHC-P

Basic Information

Specificity
Human, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
lymphocyte antigen 75
Introduction
Diseases associated with LY75 include Pneumonic Plague and Lipid Pneumonia. Among its related pathways are Dendritic Cells Developmental Lineage Pathway. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is LY75-CD302.
Entrez Gene ID
Human4065
Rat499800
UniProt ID
HumanO60449
RatD3ZQK8
Alternative Names
CD205; LY-75; CLEC13B; DEC-205; GP200-MR6
Function
Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity).
Causes reduced proliferation of B-lymphocytes.
Biological Process
EndocytosisIEA:UniProtKB-KW
Immune responseManual Assertion Based On ExperimentTAS:ProtInc
Inflammatory responseManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
Topology
Extracellular: 28-1666
Helical: 1667-1691
Cytoplasmic: 1692-1722
PTM
N-glycosylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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