Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-KIR2DS4 Recombinant Antibody (CBYY-C0379) (CBMAB-C1290-YY)


See all KIR2DS4 antibodies
Online Inquiry

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYY-C0379
Antibody Isotype
IgG2b
Application
ELISA, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Concentration
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Short Cytoplasmic Tail 4
Entrez Gene ID
3809
UniProt ID
P43632
Alternative Names
Cytochrome P450 Family 7 Subfamily B Member 1; Cytochrome P450, Subfamily VIIB (Oxysterol 7 Alpha-Hydroxylase), Polypeptide 1; Oxysterol 7-Alpha-Hydroxylase; Cytochrome P450 7B1; Cytochrome P450, Family 7, Subfamily B, Polypeptide 1; Spastic Paraplegia 5A (Autosomal Recessive);
Function
Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
Cellular Location
Cell membrane
Topology
Extracellular: 22-245
Helical: 246-265
Cytoplasmic: 266-304
More Infomation

Gowdavally, S., Tsamadou, C., Platzbecker, U., Sala, E., Valerius, T., Klein, S., ... & Fuerst, D. (2023). KIR2DS4 and Its Variant KIR1D in KIR-AA Genotype Donors Showed Differential Survival Impact in Patients with Lymphoid Disease after HLA-Matched Unrelated Hematopoietic Stem Cell Transplantation. Transplantation and Cellular Therapy.

Barani, S., Taghipour, M., & Ghaderi, A. (2020). Positive association of Bx genotype, KIR2L5, KIR2DS5 and full-length KIR2DS4 with the risk of meningioma. Immunobiology, 225(2), 151900.

Barani, S., Khademi, B., & Ghaderi, A. (2020). KIR2DS4, KIR2DL2, and KIR2DS4del are linked with basaloid tumors, lymph node metastasis, advanced stage and metastatic risk in head and neck squamous cell carcinoma. Experimental and Molecular Pathology, 112, 104345.

An, K., Li, B., Luo, C., Wang, J., Luo, C., & Chen, J. (2020). The impact of donor full‐length KIR2DS4 in the development of acute and chronic GVHD after unrelated allogeneic HSCT. Pediatric Transplantation, 24(6), e13728.

Sim, M. J., Rajagopalan, S., Altmann, D. M., Boyton, R. J., Sun, P. D., & Long, E. O. (2019). Human NK cell receptor KIR2DS4 detects a conserved bacterial epitope presented by HLA-C. Proceedings of the National Academy of Sciences, 116(26), 12964-12973.

Schenk, A., Pulverer, W., Koliamitra, C., Bauer, C. J., Ilic, S., Heer, R., ... & Zimmer, P. (2019). Acute exercise increases the expression of KIR2DS4 by promoter demethylation in NK cells. International journal of sports medicine, 40(01), 62-70.

Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-KIR2DS4 Recombinant Antibody (CBYY-C0379)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry