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Mouse Anti-HSV-2 gD Recombinant Antibody (CBMW-H0247) (CBMAB-V208-0272-FY)


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Summary

Host Animal
Mouse
Specificity
HSV
Clone
CBMW-H0247
Antibody Isotype
IgG
Application
ELISA

Basic Information

Immunogen
Herpes Simplex Virus II Glycoprotein D (gD)
Specificity
HSV
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Human Herpesvirus 2 Glycoprotein D
Introduction
Herpesviridae is a large family of DNA viruses that cause diseases in animals, including humans. The members of this family are also known as herpesviruses. The family name is derived from the Greek word herpein ("to creep"), referring to the latent, recurring infections typical of this group of viruses. Herpesviridae can cause latent or lytic infections.
UniProt ID
P03172
Alternative Names
HSV-2 gD; Herpes simplex virus 2; HSV-2; gD; Glycoprotein D
Function
Envelope glycoprotein that binds to the potential host cell entry receptors TNFRSF14/HVEM and NECTIN1. May trigger fusion with host membrane, by recruiting the fusion machinery composed of gB and gH/gL (By similarity).
Biological Process
Coreceptor-mediated virion attachment to host cell Source: BHF-UCL
Entry receptor-mediated virion attachment to host cell Source: UniProtKB-KW
Fusion of virus membrane with host plasma membrane Source: BHF-UCL
Cellular Location
Virion membrane. During virion morphogenesis, this protein probably accumulates in the endosomes and trans-Golgi where secondary envelopment occurs.
Topology
Virion surface: 26-339
Helical: 340-363
Intravirion: 364-393
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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