Mouse Anti-GNG2 Recombinant Antibody (CBLG1-1418) (CBMAB-G4146-LY)

See all GNG2 antibodies

Online Inquiry

Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

CBLG1-1418

Antibody Isotype

IgG1

Application

Basic Information

Specificity

Human

Antibody Isotype

IgG1

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Concentration

1 mg/mL

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

guanine nucleotide binding protein (G protein), gamma 2

Introduction

This gene encodes one of the gamma subunits of a guanine nucleotide-binding protein. Such proteins are involved in signaling mechanisms across membranes. Various subunits forms heterodimers which then interact with the different signal molecules. [provided by RefSeq, Aug 2011]

Entrez Gene ID

54331

UniProt ID

P59768

Alternative Names

G Protein Subunit Gamma 2; Guanine Nucleotide Binding Protein (G Protein); Gamma 2; G Gamma-I;

Function

Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).

Biological Process

Adenylate cyclase-activating dopamine receptor signaling pathway Source: BHF-UCL
Cellular response to catecholamine stimulus Source: BHF-UCL
Cellular response to prostaglandin E stimulus Source: BHF-UCL
G protein-coupled receptor signaling pathway Source: GO_Central

Cellular Location

Cell membrane

More Infomation

References

Zhao, A., Li, D., Mao, X., Yang, M., Deng, W., Hu, W., ... & Li, L. (2022). GNG2 acts as a tumor suppressor in breast cancer through stimulating MRAS signaling. Cell Death & Disease, 13(3), 260.

Chen, S., Huang, M., & Hu, X. (2021). Interference with KCNJ2 inhibits proliferation, migration and EMT progression of apillary thyroid carcinoma cells by upregulating GNG2 expression. Molecular Medicine Reports, 24(3), 1-10.

Guo, X., Zou, X., Zhang, L. B., Peng, J., Liu, R., & Tang, H. J. (2020). Nalbuphine Suppressed Cell Proliferation, Migration, and Epithelial-Mesenchymal Transition of Lung Cancer Cells via Up-Regulating G Protein Subunit Gamma 2. Journal of Biomaterials and Tissue Engineering, 10(9), 1272-1280.

Gan, S., Pan, Y., & Mao, J. (2019). miR-30a-GNG2 and miR-15b-ACSS2 interaction pairs may be potentially crucial for development of abdominal aortic aneurysm by influencing inflammation. DNA and Cell Biology, 38(12), 1540-1556.

Feng, Y., Su, Y., Ma, C., Jing, Z., Yang, X., Zhang, D., ... & Wei, J. (2019). 3′ UTR variants of TNS3, PHLDB1, NTN4, and GNG2 genes are associated with IgA nephropathy risk in Chinese Han population. International immunopharmacology, 71, 295-300.

Q & As

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Review & reward

Have you used Mouse Anti-GNG2 Recombinant Antibody (CBLG1-1418)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-GNG2 Recombinant Antibody (CBFYH-0404)

Mouse Anti-GNG2 Recombinant Antibody (CBLG1-1419)

Mouse Anti-GNG2 Recombinant Antibody (11F6)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email: