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Mouse Anti-GABPA Antibody (2G3) (CBMAB-0403-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2G3
Antibody Isotype
IgG2b
Application
IP, MA

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
GA binding protein transcription factor subunit alpha
Introduction
GABPA (GA-binding protein alpha chain) is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. GABPA is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function Since it shares identity with a subunit encoding the nuclear respiratory factor 2 gene. GABPA also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene.
Entrez Gene ID
2551
UniProt ID
Q06546
Alternative Names
E4TF1-60; E4TF1A; NFT2; NRF2; NRF2A
Function
Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene.
Biological Process
Blastocyst formation Source: Ensembl
Cell differentiation Source: GO_Central
Cellular response to dopamine Source: CAFA
Negative regulation of megakaryocyte differentiation Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: Ensembl
Positive regulation of gene expression Source: CAFA
Positive regulation of transcription by RNA polymerase II Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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