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Mouse Anti-ERP44 Recombinant Antibody (3C7) (CBMAB-A9678-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3C7
Antibody Isotype
IgG2b, κ
Application
WB, ELISA

Basic Information

Immunogen
TXNDC4 (AAH05374, 30 a.a. ~ 406 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Endoplasmic Reticulum Protein 44
Entrez Gene ID
23071
UniProt ID
Q9BS26
Alternative Names
ERP44; KIAA0573
Research Area
Mediates thiol-dependent retention in the early secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. Inhibits the calcium channel activity of ITPR1. May have a role in the control of oxidative protein folding in the endoplasmic reticulum. Required to retain ERO1A and ERO1B in the endoplasmic reticulum.
Biological Process
Cell redox homeostasis Source: UniProtKB
Glycoprotein metabolic process Source: UniProtKB
Protein folding Source: UniProtKB
Response to endoplasmic reticulum stress Source: UniProtKB
Response to unfolded protein Source: UniProtKB
Cellular Location
Endoplasmic reticulum lumen
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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