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Mouse Anti-DMBX1 Recombinant Antibody (CBXO-0337) (CBMAB-O0164-CQ)


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Summary

Host Animal
Mouse
Specificity
Mouse, Rat, Human
Clone
CBXO-0337
Antibody Isotype
IgG
Application
WB, IP, IF, ELISA

Basic Information

Specificity
Mouse, Rat, Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
diencephalon/mesencephalon homeobox 1
Introduction
This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. Two transcript variants encoding distinct isoforms have been identified for this gene.
Entrez Gene ID
Human127343
Mouse140477
Rat313512
UniProt ID
HumanQ8NFW5
MouseQ91ZK4
RatD3ZMA3
Alternative Names
Diencephalon/Mesencephalon Homeobox 1; Paired-Like Homeobox Protein DMBX1; Orthodenticle Homolog 3; OTX3; PAXB; MBX; Diencephalon/Mesencephalon Homeobox Protein 1; Orthodenticle Homolog 3 (Drosophila); Homeoprotein MBX
Function
Functions as a transcriptional repressor. May repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence. Required for brain development (By similarity).
Biological Process
Adult feeding behavior Source: Ensembl
Adult locomotory behavior Source: Ensembl
Brain development Source: UniProtKB
Central nervous system development Source: UniProtKB
Developmental growth Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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