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Mouse Anti-DMBX1 Monoclonal Antibody (1A9) (CBMAB-1033-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1A9
Antibody Isotype
IgG
Application
ELISA

Basic Information

Immunogen
Partial recombinant protein DMBX1 (NP_671725, aa 1-88) with GST tag
Specificity
Human
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
>95%, as determined by SDS-PAGE analysis
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
diencephalon/mesencephalon homeobox 1
Introduction
DMBX1 is a transcription factor that belongs to a member of the bicoid sub-family of homeodomain-containing transcription factors. DMBX1 may play a role in brain and sensory organ development.
Entrez Gene ID
127343
UniProt ID
Q8NFW5
Alternative Names
MBX; OTX3; PAXB
Function
Functions as a transcriptional repressor. May repress OTX2-mediated transactivation by forming a heterodimer with OTX2 on the P3C (5'-TAATCCGATTA-3') sequence. Required for brain development (By similarity).
Biological Process
Adult feeding behavior Source: Ensembl
Adult locomotory behavior Source: Ensembl
Brain development Source: UniProtKB
Central nervous system development Source: UniProtKB
Developmental growth Source: UniProtKB
Negative regulation of transcription, DNA-templated Source: UniProtKB
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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